Nanomaterials in the Food Supply Chain

Research, innovation and security

The ECSIN laboratory supports companies in the development and assessment of the safety of innovative products in the food, nutraceutical and packaging sectors, maximizing efficiency and ensuring safety.

The use of nanotechnology in the food sector throughout the food supply chain is constantly growing. The interest arises from the possibility of improving the nutritive, technical and functional properties of ingredients and packaging, such as the stability and bioavailability of nutrients and nutraceuticals, or to implement the traceability of food to consumption.

ECAMRICERT-ECSIN helps companies in the development and evaluation of nanotechnologies, responding to industry regulations (eg Reg. (EU) 2283/2015 (Novel Food), Reg. 10/2011 (plastics). nanomaterial point of view from a chemical point of view, determines its effectiveness and functionality, and evaluates its occupational safety and consumer protection.

ECAMRICERT-ECSIN operates taking care of the entire management of the project, from development to regulatory support, or responding to specific customer requirements, providing the design experience and know-how gained over the years.

  • Product development
  • Check and quality control of production and product
  • Agribusiness
  • Dietary supplements and products
  • Materials and objects in contact with food
  • pharmaceutical
  • Cosmetics
  • Nanomaterial characterization (TEM-EDX, BET, A4F, ICP-MS, and DLS)
  • Evaluation of bioaccessibility and bioavailability
  • Determination of transport mechanisms – absorption / diffusion / secretion (epi-fluorescence and confocal microscopy, apparent permeability, identification of active transport mechanisms mediated by P-gp)
  • Mechanisms of action (molecular biology and proteomics, PCR, RT-PCR, electrophoresis, western blot, ELISA)
  • Safety of additives in nanoform and new formulations
  • Pre-normative and normative analysis
  • Technological development and choice of materials
  • Nanomaterial chemical and physical characterization and packaging
  • Migration studies in food simulants
  • Total and specific migration from objects in contact with food under realistic conditions
  • Antimicrobial efficacy
  • Chemical identification and quantification of released substances
  • Evaluation of safety and regulatory support
Definition of nanomaterialMatrices: raw material, food matrices, food simulants, digestive fluids, materials in contact with foodRacc. Comm. 2011/696 / EU (Definition) Reg. (CE) 1333/2008 (Additives) EU Reg.) 1160 / 2011 (Labeling) Reg. (UE) 2283/2015 (New foods) Reg. (EU) 10/2011 (Plastics) Reg. (CE) 450/2009 (Active and intelligent packaging)
EfficiencyBioaccessibility Bioavailability Loading capacity of the active ingredient Release profile of the active substance Stability of the on going and accelerated formulation Functionality Release Stability of the active substance Antimicrobial effectReg. (CE) 1924/2006 (Health and nutritional claims) Reg. (CE) 450/2009 (active and intelligent packaging) Reg. (EU) 10/2011 (plastics) Reg. (EU) 528/2012 (biocidal products )
SafetyBarrier integrity Cytotoxicity Genotoxicity Mutagenicity Carcinogenicity Inflammatory response Total and specific migration Persistence of the nanoform ToxicityEFSA Guidelines (2011) Reg. (CE) 1333/2008 (Additives) Reg. (EU) 231/2012 (Additive specifications) Reg. (EU) 2283/2015 (New foods) Reg. (EU) 10/2011 ( Plastics) Reg. (CE) 450/2009 (Active and intelligent packaging)


Federico Benetti: