R&D

ECAMRICERT, thanks its technicians’ competence, has developed across-the-board experiences and abilities in strategic research and innovation during time. In this context it usually conducts R&D activities, involving all the different sectors in projects co-subsidized on a regional (POR Veneto and FSE funds), national and European (Horizon 2020) level. ECAMRICERT accompanies through this growth its clients as well, planning research activities, selecting the best European and national university centers, setting up funded educational paths, all of which is oriented to a constant improvement of both products and processes.

European


  1. European license “Diffractive optic element”
  2. European license “Procedure for the production of flour-based bread in a box and a fermented composite of milk and pure bacteria culture origin”

National


  1. Italian license “Method to identify in time bacteria and milk fungi colonies”
  2. Italian license “Process for the production of cement conglomerates made of industrial wastes of marble loam with the addiction of wastes of exhausted ground coffee”

European


The B-Impact (Bronze-Improved non-hazardous Patina CoaTings) project aimed to develop innovative protective eco-compatible and non-dangerous upholstery, to protect bronze surfaces exposed to the external environment. In fact, bronze artifacts and monuments exposed to open-air are subject to degradation processes, especially in polluted environments. The process of corrosion and the degradation of the surface’s stability and look take place on new exposition bronze surfaces as well as ‘old’ bronze surfaces. Their protection and maintenance is a great challenge, which requires a constant economic effort. In the range of Cultural Goods conservation, ‘ready-to-go’ customized formulations were found, based on advanced protection strategies to reduce the maintenance costs, as well as effective conservation solutions for the final customers, including local authorities and other sectors (architects, artists, museums, etc.)

Begun March 2015, finished March 2017

The innovative and economic potential of MNM (Manufactured Nano Materials) is threatened by a limited comprehension of the related EHS (Environment, Health, and Safe). While the data of toxicity are always available, the importance the legislator’s eyes is often unclear or undemonstrated. The restriction of commercialization times of new MNMs entails the necessity of an urgent action by regulation authorities. NANoREG is the first project of the 7th PQ to give necessary answers to regulators and legislators about EHS, connecting them to a scientific data and testing methods evaluation. On the base of questions and requisites given by legislators and stakeholders, NANoREG retailed: answers and solutions from existing data, integrated with new knowledges; a series of procedures with instruments for MNM’s risk evaluation, characterization, toxicity tests and exposition measurements; new testing strategies fitting the requirements of innovation; a close collaboration between authorities, industry and science which led to new efficient and practically applicable approaches of risk management for MNMs and products containing MNMs. The interdisciplinary approach, involving the three main interested subjects (regulation, industry and science) significantly contributed to decrease the risks coming from MNMs in industrial and consumption products.

http://www.nanoreg.eu/

Begun March 2013, finished December 2016

Begun February 2015, finished January 2017

Despite the increasing number of macro-molecules with a potential impact on the treatment of lethal systemic diseases, those therapies could not satisfy the expectations, because they cannot be given in the most efficient way cost-wise and with the maximum reception of the patient: oral. Availability of a form of oral administration contributes to a notable improvement of classical therapies and an increase in the number of new viable therapies. To achieve this, the final objective of Trans-Int was to project some nano-carrier specifically adapted to face the gastrointestinal ecosystem and utilize them to develop new oral nano-medicines for socio-economic high-impact diseases (such as metabolic diseases, painkillers). The main concept of Trans-Int is rational project of oral nano-medicines, based on safety, mechanics, bioengineering (multi-functional nano-carriers: high useful load, protection from drugs, efficient transportation of drugs, controlled release) and pharmaceutical technologies standards (deductible technology and stability). The project began with platforms of nano-carriers on which partners were free to operate: nano-capsules, nano-particles, micelles made of combinations of lipids, polypeptides and polysaccharides, until optimizing and redefining selected nano carriers. The project allowed creating: a prototype of oral nano carrier with a complete package of GLP-tox, which might be applied to deliver a relevant number of peptides molecules; a nanomedicine satisfying the profile criteria of the product’s target, with a complete pre-clinic evaluation package; a significant integrative knowledge on possibility and potential of oral nano-pipes and nano-pharmaceutical products

http://www.trans-int.eu/

Began May 2012, finished April 2017

One of the biggest challenges for legislators in the ever-evolving landscape of new nano-materials is how to project and implement a normative process strong enough to manage a system of manufactural nano-materials (MNM) that rapidly diversifies with time. Nevertheless, it is not only a matter of complexity, since nano-materials are a problem to legislators also because of their validity of data decreasing with time, as said by the notorious principle of half-life of facts (Samuel Arbesman, 2012). This means that what is an accepted truth now, will not be valid between 20 or 30 years. The challenge is setting up a normative system flexible enough to be able to face new goals and requirements in the future, and in this development and introduction of Safe by Design (SbD) principles will help. Credibility of such a normative system, supported by the implementation of SbDs, is essential to industry, which even though accepts the necessity of an adequate regulation, requires it to be persecuted in an economically convenient and rapid. The NanoReg2 project, built around the challenge of pairing SbDs to the normative process, will prove and establish SbD as main cornerstone in validation of a new manufactural nano-material. It is widely recognized by industries and regulation agencies, which are immediately necessary grouping strategies for nano-materials. The ECETOC formed a task force on nano-materials grouping and a group is working on the categorization NM inside OCSE’s WPMN. However, until now it was impossible to set reliable group concepts and accepted rules. Grouping concepts developed by NanoReg2 can be considered a great innovation; therefore, orientation documents on NM grouping will not only support new industries or regulation agencies, but would also support the commercial launch of a new NM

http://www.nanoreg2.eu/

Began September 2015, finished August 2018

National


The SEAL (Smart & safe Energy-aware Assisted Living) project has the goal of developing new knowledges, products and services to introduce systems for domotic environments (AAL, Ambient Assisted Living) in the market, which could services orientated to safety (for people and environments) and sustainability (in terms of energetic efficiency). In this, SEAL falls into the topic related to Smart Cities development, which provides for the integration of unities (on a building, structure, community level) operating smart themselves.

The project unfolds in 7 Objectives of Realization (OR):

OR1- Materials and processes: innovative materials and transformation technologies

OR2- Devices: innovative mechatronic devices

OR3- Activation: highly efficient and reliable electric activators

OR4- Device network: domotic systems to improve energetic management, environmental comfort and air quality, accesses safety and control

OR5- CCTV network: networks of cameras for video-monitoring and users assistance

OR6- Data and systems: infrastructure of domotic residential systems or AAL, fusion of data provided by mixed sensors

OR7- Experimenting: experimenting prototypes in PAs, with system performance test

The innovative services were situated in user’s safety sectors and in energetically efficient buildings management (two of the settings considered more interesting to potential users of domotic systems)

SEAL project’s ultimate goal was developing methodologies for intelligent systems, based on mutual interaction between devices (CCTV and sensors networks and auctioning devices, though as logical elements not necessarily physically distinct), in order to allow mixed multi-agent network build-up safety-aimed (for people and environments) and sustainability (in terms of energetic efficiency and aware utilization of resources). To accomplish that objective, innovative devices were created and also a general system infrastructure to elaborate the info shared on the web. This is based on a non-owned, open register, able to manage the flow of data, to which the systems (devices, sensors and activators) interface as plug-ins, extracting or submitting information clearly to the user of said services. In order to accomplish the ultimate goal, advanced solutions and applications were developed in the following research fields: innovative production materials and processes, highly performing and efficient electric activations for mechatronic systems, sensors and actuators integrated networks miscellaneously distributed, CCTV networks, socio-sanitary and juridical aspects for AAL systems.

Began March 2013, finished December 2016

Regional


Woody plants’ endotherapy consists in introducing phytohealth products distinguished by systemic features directly in the trunk through injection and taking advantage of the relocation of those substances through lymphatic system with the aim of treat every part of the tree.

In urban areas, the endotherapy represents the best solutions, being that it does not expose the operator nor the inhabitants to the dispersion of phytomedicines, typical of other treatments such as sprayings, paintings and injection to the soil. Everything is done with the maximum efficiency from a utilized product quantity point of view and an almost eliminated drift in the surrounding environment. The firm is extremely sensitive to that topic, so much that the EU will most likely dictate to make public green treatments exclusive for endotherapy from 2014.

Injection to the trunk or roots by means of invasive pressure systems is not a new operation, considering that the first jobs with forced introduction are bonded with studies about tree feeding from the ‘30s (Collison et al., 1932). Nevertheless, this method causes the damaging of the tree, because of the notable number of holes made with electric drills (tissue removal damage, shift warming, embolization and creation of continuity for possible pathogens).

With the goal of avoiding such alterations was born BITE (Blade for Infusion in TrEes), an invention by the University of Padua. Its innovative lenticular blade inserts between fibers without removing woody tissues and allowing a quick cicatrization. With such method it is not necessary to implement artificial pressure and instead choose an injection related to the Venturi effect, created by the blade and to the natural absorption to an atmospheric pressure, which speed depends on the plant’s features, phenological phase and other physiologic parameters (eg. leaves mass and health state) and conditions. There are six active principles currently authorized to endotherapy in Italy, covering not enough of the guest-parasitic couple spectrum: thiabendazol (a fungicide only authorized against plane tree’s anthracnosis), azadiractine, clorpirifos-metil, imidacropil and abamectine (insecticides and acaruscides) and glifosate (a herbicide). Due to the extremely lacking availability of efficient formulates, with this project we faced a multi-year research plan, focused on the optimization of new endotherpicists on a superior level of specificity. The main point of the project was verifying the phyto-medicines’ active principles (phyto-regulators, dissecants, fungicides and insecticides) already authorized in Europe and potentially the study about molecules not tested yet, together with the experimenting of transmissives and formulations that make them alike to lymph (eg. pH, salinity…) and allow the functioning of the treatment. Such solutions have been tested on the field for the single vegetal species and the associated pathogen. All inside of a global perspective of overview of the tree-pathogen-environment system thanks to the analysis of the environmental characteristics (such as radiation, windiness, air temperature and humidity, stomatic resistance, degree of soil saturation…) at the time of treatment, with the goal of obtaining the most effective and versatile combinations. Therefore, the application fields were more different, from public green to orchards, to research of the most eco-compatible solutions. The analysis of phyto-medicines’ remains in leaves and fruits, with treatment marking times, were the key to select the most effective combination from a point of view of the disease’s annihilation, but with shorter marking times.

Began February 2015, finished April 2016

Development of integrated approach for innovation, efficiency and safety in food range.

The project overviews the context of smart agrifood specialization as developed in Veneto’s regional strategy s3. Starting from the analysis of weakness points of the sector in region, such as the preponderating of small productive entities, and the consequent difficulty to understand innovation opportunities, the project aims to develop useful instruments for PMIs to increase in a simple, rapid and sustainable way the innovation of food products. Especially, activities are focused on the ‘food nutrition, health and safety’ development trajectory. Between these three topics, safety represents an aspect considered the most important by firms in general, as indicated by Veneto’s RIS3 report (page 95). Aiming to evaluate the safety of new ingredients and formulations, the project will develop an integrated and automatized prototype of an in vitro human digestive model, projected and validated according to European standards and suiting law regulations. From the innovation point of view, nanotechnologies will be applied as enabling technologies. From the PMIs point of view, nanotechnologies allow to innovate transformation processes, and therefore valorizing vegetal production, niche ones as well, through a defined differentiation, compared to products already present on the market. Innovative ingredients find their application, for example, in food integrators, functional food, and to a special medical purpose, categories of products with a great benefit. For what concerns innovation drivers and referring to European politics of active aging, malnutrition represents one of the main causes of elders’ fragility and decrease in their cognitive capacities. The use of functional food and integrators is an integral part of the NUTRILIVE project (Illario et al., 2016) for active aging. The development and verifying the efficiency and safety of specific products, with a high bio-availability and calibrated for nutritional and health conditions, may be a deciding factor in improving the nutritional status, completing a healthy, balanced diet and at the same time helping to prevent functional and cognitive decay.